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v1.17.0

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@ivazquez ivazquez released this 08 Sep 10:28
· 109 commits to master since this release

changed the way SNV priors are computed:

  • if CNA given: SNV prior informed by CNA posterior
  • if CNA+BAF given, SNV prior informed by BAF+CNA posterior
  • if SNV only and --max-tcn not given, assumes all chr to be all-normal, mean total c.n. to be normal; SNV prior parameters can be learned with --learn-priors 1.
  • if SNV only and --max-tcn [int/file] is given, this data is used to fix the total c.n. per chr and subclone; mean total c.n. is calculated on the fly; SNV prior parameters can be learned with --learn-priors 1.
  • if SNV only and --max-tcn [int/file] and --avail-cn [file] are given, SNV prior is calculated according to c.n. availability.

more changes

  • changed option --copynumber [file] to --mean-tcn [file]
  • new option --avail-cn [file]
  • changed option --maxcn [int:4] to --max-tcn [file/int]
  • changed option --snv-err [double] to --snv-fpfreq [double]
  • changed option --snv-fpr [double] to --snv-fprate [double]
  • output file *used-tcn.txt to *used_mean_tcn.txt
  • output file *copynumber.txt to *mean_tcn.txt
  • new output file *available_cn.txt
  • changed sample to chr in cloneHD output files
  • slimmed down output of --print-options.
  • split clone.cpp into components clone-*.cpp
  • split off cloneHD-inference.cpp
  • new Makefile