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@katsikora katsikora released this 27 Feb 16:46
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v1.0.0
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Learn about vigilant mode.

This is a light pipeline version, starting from sequencing reads. Auto or user-directed read trimming is performed. Reads are mapped to a reference genome stored in local repo with bwa-meth, MethylDackel is used for methylation extraction, and metilene for DMR colling. Single cytosine as well as genomic interval aggregate stats are performed with limma on logit-transformed beta values. A quality report with bisultfite coversion rates, mapping rates, coverage and methylation bias is produced.

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