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Reproducible Machine Learning Classifier Analysis

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@gwaybio gwaybio released this 30 Oct 15:16
· 36 commits to master since this release
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Release Version 1.0

2018 Gregory Way, Jo Lynne Harenza, John Maris

This release includes a complete reproducible analysis pipeline for the application of supervised machine learning classifiers to detect Ras activation, NF1 inactivation, and TP53 inactivation in pediatric PDX RNAseq data.

The classifiers were originally trained on TCGA PanCanAtlas data (as described in Way et al. 2018 and Knijnenburg et al. 2018).