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mcupak committed Jun 14, 2016
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12 changes: 6 additions & 6 deletions README.md
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* [Technologies](#technologies)

##What it is
This project contains BDK (beacon development kit) for Python developers. It provides a skeleton of a simple beacon allowing the developers to plug in their own data/functionality. The API makes sure the response produced is compatible with what the Beacon of Beacons can consume.
This project contains BDK (beacon development kit) for Python developers. It provides a skeleton of a simple beacon allowing the developers to plug in their own data/functionality. The API makes sure the response produced is compatible with the [Beacon API](https://github.com/ga4gh/beacon-team/).

##System requirements
All you need to build this project is Python and Flask web framework. If you're running Linux, OS X or Windows with cygwin support, the following commands should be enough to set up Flask (the process is a bit different with the native version of Python on Windows):
All you need to build this project is Python 2 and Flask web framework. If you're running Linux, OS X or Windows with cygwin support, the following commands should be enough to set up Flask (the process is a bit different with the native version of Python on Windows):

$ cd todo-api
$ pip install virtualenv
$ virtualenv flask
$ flask/bin/pip install flask

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The API takes care of the rest and provides the following endpoints when you start your beacon:

http://127.0.0.1:5000/beacon-python/info - information about your beacon
http://127.0.0.1:5000/beacon-python - information about your beacon
http://127.0.0.1:5000/beacon-python/query - access to query service

Query example:

GET http://127.0.0.1:5000/beacon-python/query?chrom=15&pos=41087870&allele=A&ref=hg19
GET http://127.0.0.1:5000/beacon-python/query?referenceName=1&start=1000&referenceBases=A&alternateBases=T&assemblyId=GRCh37&datasetIds=&includeDatasetResponses=true

##Technologies
Python, Flask.
Python 2, Flask.
237 changes: 85 additions & 152 deletions beacon.py
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#!flask/bin/python

'''
"""
The MIT License
Copyright 2014 DNAstack.
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LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
THE SOFTWARE.
'''
"""

from flask import Flask, jsonify, request


class IncompleteQuery(Exception):
status_code = 400

def __init__(self, message, status_code=None, payload=None, ErrorResource=None, query=None, beacon_id=None):
Exception.__init__(self)
self.message = message
if status_code is not None:
self.status_code = status_code
self.payload = payload
self.ErrorResource = ErrorResource
self.query = query
self.beacon_id = beacon_id

def to_dict(self):
rv = dict(self.payload or ())
rv["beacon"] = self.beacon_id
rv["query"] = self.query
rv['error'] = self.ErrorResource
return rv


app = Flask(__name__)

# --------------- Information endpont (start) --------------------#

# TODO: override with the details of your beacon

########### DataSetResource for beacon details ############

# required field(s): name
DataUseRequirementResource = {
'name': u'example name',
'description': u'example description'
BeaconAlleleRequest = {
'referenceName': u'', # required
'start': 0, # required
'referenceBases': u'', # required
'alternateBases': u'', # required
'assemblyId': '', # required
'datasetIds': [], # optional
'includeDatasetResponses': False, # optional
}

# required field(s): variants
DataSizeResource = {
'variants': 1, # integer
'samples': 1 # integer
BeaconDataset = {
'id': u'', # required
'name': u'', # required
'description': u'', # optional
'assemblyId': u'', # required
'createDateTime': u'', # required
'updateDateTime': u'', # required
'version': u'', # optional
'variantCount': 1, # optional
'callCount': 1, # optional
'sampleCount': 1, # optional
'externalUrl': u'', # optional
'info': {} # optional
}

# required field(s): category
DataUseResource = {
'category': u'example use category',
'description': u'example description',
'requirements': [
DataUseRequirementResource
]
BeaconOrganization = {
'id': u'', # required
'name': u'', # required
'description': u'', # optional
'address': u'', # optional
'welcomeUrl': u'', # optional
'contactUrl': u'', # optional
'logoUrl': u'', # optional
'info': {} # optional
}

# required field(s): id
DataSetResource = {
'id': u'example Id',
'description': u'dataset description',
'reference': u'reference genome',
'size': DataSizeResource, # Dimensions of the data set (required if the beacon reports allele frequencies)
'data_uses': [
DataUseResource # Data use limitations
]
Beacon = {
'id': u'', # required
'name': u'', # required
'apiVersion': u'0.3', # required
'organization': BeaconOrganization, # required
'description': u'', # optional
'version': u'', # optional
'welconeUrl': u'', # optional
'alternativeUrl': u'', # optional
'createDateTime': u'', # optional
'updateDateTime': u'', # optional
'datasets': [ # optional
BeaconDataset
],
'sampleAlleleRequests': [ # optional
BeaconAlleleRequest # Examples of interesting queries
],
'info': {}
}

########### QueryResource for beacon details ###############
BeaconError = {
'errorCode': 400, # required
'message': u'' # optional
}

# required field(s): allele, chromosome, position, reference
QueryResource = {
'allele': u'allele string',
'chromosome': u'chromosome Id',
'position': 1, # integer
'reference': u'genome Id',
'dataset_id': u'dataset Id'
BeaconDatasetAlleleResponse = {
'datasetId': u'', # required
'exists': True, # optional (required in no-error cases)
'error': None, # optional (required in case of an error)
'frequency': u'', # optional
'variantCount': 1, # optional
'callCount': 1, # optional
'sampleCount': 1, # optional
'note': u'', # optional
'externalUrl': u'', # optional
'info': {} # optional
}

################### Beacon details #########################

# required field(s): id, name, organization, api
beacon = {
'id': u'foo',
'name': u'bar',
'organization': u'org',
'api': u'0.1/0.2',
'description': u'beacon description',
'datasets': [
DataSetResource # Datasets served by the beacon
],
'homepage': u'http://dnastack.com/ga4gh/bob/',
'email': u'[email protected]',
'auth': u'oauth2', # OAUTH2, defaults to none
'queries': [
QueryResource # Examples of interesting queries
BeaconAlleleResponse = {
'beaconId': u'', # required
'exists': True, # optional (required in no-error cases)
'error': None, # optional (required in case of an error)
'alleleRequest': BeaconAlleleRequest, # optional
'datasetAlleleResponses': [ # optional
BeaconDatasetAlleleResponse
]
}


# --------------- Information endpoint (end) ----------------------#

# info function
@app.route('/beacon-python/info', methods=['GET'])
# TODO: override with the details of your beacon (see https://github.com/ga4gh/beacon-team/ for more details)
@app.route('/beacon-python/', methods=['GET'])
def info():
return jsonify(beacon)
return jsonify(Beacon)


# query function
# TODO: plug in the functionality of your beacon
# TODO: plug in the functionality of your beacon (see https://github.com/ga4gh/beacon-team/ for more details)
@app.route('/beacon-python/query', methods=['GET'])
def query():
# parse query
chromosome = request.args.get('chrom')
position = long(request.args.get('pos'))
allele = request.args.get('allele')
reference = request.args.get('ref')
dataset = request.args.get('dataset') if 'dataset' in request.args else beacon['datasets'][0]['id']

# ---- TODO: override with the necessary response details ----#

############## AlleleResource for response ###############

# required field(s): allele
AlleleResource = {
'allele': allele,
'frequency': 0.5 # double between 0 & 1
}

############# ErrorResource for response #################

# required field(s): name
ErrorResource = {
'name': u'error name/code',
'description': u'error message'
}

################### Response object #########################

# generate response
# required field(s): exists
response = {
'exists': True,
'observed': 0, # integer, min 0
'alleles': [
AlleleResource
],
'info': u'response information',
}

query = {
'chromosome': chromosome,
'position': position,
'allele': allele,
'reference': reference,
'dataset_id': dataset
}

if query['chromosome'] is None or query['position'] is None or query['allele'] is None or query[
'reference'] is None:
ErrorResource['description'] = 'Required parameters are missing'
ErrorResource['name'] = 'Incomplete Query'
raise IncompleteQuery('IncompleteQuery', status_code=410, ErrorResource=ErrorResource, query=query,
beacon_id=beacon["id"])

# --------------------------------------------------------------#

return jsonify({"beacon": beacon['id'], "query": query, "response": response})


# info function
@app.route('/beacon-python/', methods=['GET'])
def welcome():
return 'WELCOME!!! Beacon of Beacons Project (BoB) provides a unified REST API to publicly available GA4GH Beacons. BoB standardizes the way beacons are accessed and aggregates their results, thus addressing one of the missing parts of the Beacon project itself. BoB was designed with ease of programmatic access in mind. It provides XML, JSON and plaintext responses to accommodate needs of all the clients across all the programming languages. The API to use is determined using the header supplied by the client in its GET request, e.g.: "Accept: application/json".'


# required parameters missing
@app.errorhandler(IncompleteQuery)
def handle_invalid_usage(error):
response = jsonify(error.to_dict())
return response
BeaconAlleleRequest['referenceName'] = request.args.get('referenceName')
BeaconAlleleRequest['start'] = int(request.args.get('start'))
BeaconAlleleRequest['referenceBases'] = request.args.get('referenceBases')
BeaconAlleleRequest['alternateBases'] = request.args.get('alternateBases')
BeaconAlleleRequest['assemblyId'] = request.args.get('assemblyId')
BeaconAlleleRequest['datasetIds'] = request.args.getlist('datasetIds')
BeaconAlleleRequest['includeDatasetResponses'] = bool(request.args.get('includeDatasetResponses'))

return jsonify(BeaconAlleleResponse)


# page not found
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