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HOT (High-Occupancy Target) regions are defined where many different Transcription Factors bind in modENCODE ChIP-seq studies. The maximum is 87, the paper takes the top 1% (out of ~30,000). This pipeline labels all of the regions (Super hot: top 1%, Red hot: top 10%, Medium: 80%, Mild: Remainder). Data from: Regions on Ce10 from this paper: Chen, R. A. J., Stempor, P., Down, T. A., Zeiser, E., Feuer, S. K., & Ahringer, J. (2014). Extreme HOT regions are CpG-dense promoters in C. elegans and humans. Genome Research, 24(7), 1138–1146. https://doi.org/10.1101/gr.161992.113 Needs UCSC User Apps: liftOver bedToBigBed bedSort
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