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@Mathelab Mathelab released this 23 Mar 12:58
· 524 commits to main since this release
v2.2.1
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RaMP v2.2.1 is a database refresh update and data curation release.

The latest release includes additional records for LIPID MAPS, ChEBI, and WikiPathways. Releases input are:

  • HMDB v5.0 (2021-11-17)
  • Reactome v83 (Nov 2022)
  • WikiPathways v20230210 (2023-02-10)
  • KEGG from HMDB (v5.0) (2021-11-17)
  • ChEBI Release 218 (2022-02-01)
  • LidpidMAPS Release 2023-02-24

New data curation included removal of 320 metabolite id cross-reference errors found in source data. Curation is used to identify metabolite ID type cross references from data sources that incorrectly link unrelated compounds. Automated first-pass curation includes an initial check based on the monoisotopic mass associated with the ID pair being tested. ID pairs with masses that differ by greater than 10% from the smaller mass are send to a log for manual curation where verified mis-mappings are added to an exclusion list used to stop the propagation of improper ID cross references. In this build an additional step was introduced to query the chemical properties table in the RaMP database to discover additional bad ID pair cross-references that were missed by the process due to incomplete mass information for certain ID types. A second round of manual curation is used to resolve remaining ID cross reference errors.

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