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glandular epithelial cell refactor option 2 (#2452)
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* GE cells PO gland; added epi secretory cell

Made GE cells part of gland;
Added secretory epithelial cell as more general class;
Edited glandular epithelial cell hierarchy to remove any cells not in glands.  Edited names of some grouping terms.

* Removed classification excretory cell under secretory cell

* glandular cell of endometrium is a glandular epithelial cell

Also added some details on what these cells secrete.

* Updates to parathyroid gland cells

* Change cells that are not part of the gland to secretory epithelial cells, instead of glandular secretory epithelial cells

* Update cl-edit.owl

---------

Co-authored-by: CEastwood <[email protected]>
Co-authored-by: Aleix Puig <[email protected]>
Co-authored-by: Caroline Eastwood <[email protected]>
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4 people authored Oct 17, 2024
1 parent dde92b7 commit 707a393
Showing 1 changed file with 51 additions and 44 deletions.
95 changes: 51 additions & 44 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -2648,6 +2648,7 @@ Declaration(Class(obo:CL_1001608))
Declaration(Class(obo:CL_1001609))
Declaration(Class(obo:CL_1001610))
Declaration(Class(obo:CL_1001611))
Declaration(Class(obo:CL_1100001))
Declaration(Class(obo:CL_2000000))
Declaration(Class(obo:CL_2000001))
Declaration(Class(obo:CL_2000002))
Expand Down Expand Up @@ -4996,15 +4997,14 @@ AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000149 "pigment cell")
AnnotationAssertion(rdfs:label obo:CL_0000149 "visual pigment cell")
SubClassOf(obo:CL_0000149 obo:CL_0000147)

# Class: obo:CL_0000150 (glandular epithelial cell)
# Class: obo:CL_0000150 (glandular secretory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000150 "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ORCID:0000-0002-7073-9172") obo:IAO_0000115 obo:CL_0000150 "An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000150 "CALOHA:TS-2085")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000150 "FMA:86494")
AnnotationAssertion(rdfs:label obo:CL_0000150 "glandular epithelial cell")
SubClassOf(obo:CL_0000150 obo:CL_0000066)
SubClassOf(obo:CL_0000150 obo:CL_0000151)
SubClassOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0006799))
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000150 "glandular epithelial cell")
AnnotationAssertion(rdfs:label obo:CL_0000150 "glandular secretory epithelial cell")
EquivalentClasses(obo:CL_0000150 ObjectIntersectionOf(obo:CL_0000066 obo:CL_0000151 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002530)))

# Class: obo:CL_0000151 (secretory cell)

Expand Down Expand Up @@ -5130,7 +5130,7 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000164 "BTO:0003865")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000164 "FMA:62930")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000164 "MESH:D019858")
AnnotationAssertion(rdfs:label obo:CL_0000164 "enteroendocrine cell")
SubClassOf(obo:CL_0000164 obo:CL_0000150)
SubClassOf(obo:CL_0000164 obo:CL_0000066)
SubClassOf(obo:CL_0000164 obo:CL_0000163)

# Class: obo:CL_0000165 (neuroendocrine cell)
Expand Down Expand Up @@ -6372,9 +6372,8 @@ SubClassOf(obo:CL_0000318 obo:CL_0000151)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000319 "BTO:0003689")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000319 "mucous cell")
AnnotationAssertion(rdfs:label obo:CL_0000319 "mucus secreting cell")
EquivalentClasses(obo:CL_0000319 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254)))
EquivalentClasses(obo:CL_0000319 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254)))
SubClassOf(obo:CL_0000319 obo:CL_0000159)
SubClassOf(obo:CL_0000319 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254))

# Class: obo:CL_0000320 (obsolete megasporocyte)

Expand Down Expand Up @@ -7134,7 +7133,7 @@ SubClassOf(obo:CL_0000423 obo:CL_0000422)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:19783135") obo:IAO_0000115 obo:CL_0000424 "A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000424 "WBbt:0005812")
AnnotationAssertion(rdfs:label obo:CL_0000424 "excretory cell")
SubClassOf(obo:CL_0000424 obo:CL_0000151)
SubClassOf(obo:CL_0000424 obo:CL_0000000)

# Class: obo:CL_0000425 (pore cell)

Expand Down Expand Up @@ -7206,7 +7205,8 @@ AnnotationAssertion(owl:deprecated obo:CL_0000433 "true"^^xsd:boolean)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0198547684") obo:IAO_0000115 obo:CL_0000434 "A secretory cell that discharges its product without loss of cytoplasm.")
AnnotationAssertion(rdfs:label obo:CL_0000434 "eccrine cell")
SubClassOf(obo:CL_0000434 obo:CL_0000150)
SubClassOf(obo:CL_0000434 obo:CL_0000066)
SubClassOf(obo:CL_0000434 obo:CL_0000151)

# Class: obo:CL_0000435 (alkali secreting cell)

Expand Down Expand Up @@ -7302,8 +7302,9 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000446 "parathyroid gland c
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000446 "parathyroid hormone secreting cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000446 "principal cell of parathyroid gland")
AnnotationAssertion(rdfs:label obo:CL_0000446 "chief cell of parathyroid gland")
SubClassOf(obo:CL_0000446 obo:CL_0000167)
SubClassOf(obo:CL_0000446 obo:CL_0002260)
SubClassOf(obo:CL_0000446 obo:CL_0000066)
SubClassOf(obo:CL_0000446 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011197))
SubClassOf(obo:CL_0000446 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0035898))

# Class: obo:CL_0000447 (carbohydrate secreting cell)

Expand Down Expand Up @@ -7807,10 +7808,12 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000510 "BTO:0000993")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000510 "FMA:62897")
AnnotationAssertion(rdfs:label obo:CL_0000510 "paneth cell")
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000510 obo:CL_0000150)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000510 obo:CL_0000066)
SubClassOf(obo:CL_0000510 obo:CL_0000323)
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277))
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001983))
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005773))
SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005902))

# Class: obo:CL_0000511 (androgen binding protein secreting cell)

Expand Down Expand Up @@ -8854,9 +8857,7 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000622 "MESH:D061354")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000622 "acinic cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000622 "acinous cell")
AnnotationAssertion(rdfs:label obo:CL_0000622 "acinar cell")
SubClassOf(obo:CL_0000622 obo:CL_0000150)
SubClassOf(obo:CL_0000622 obo:CL_0000154)
SubClassOf(obo:CL_0000622 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009842))
EquivalentClasses(obo:CL_0000622 ObjectIntersectionOf(obo:CL_0000150 obo:CL_0000154 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0009842)))

# Class: obo:CL_0000623 (natural killer cell)

Expand Down Expand Up @@ -15611,7 +15612,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002180 "2010-08-25T03:38:51Z"
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002180 "FMA:63464")
AnnotationAssertion(rdfs:label obo:CL_0002180 "mucous cell of stomach")
EquivalentClasses(obo:CL_0002180 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000945) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070254)))
SubClassOf(obo:CL_0002180 obo:CL_0002659)

# Class: obo:CL_0002181 (mucous neck cell of gastric gland)

Expand Down Expand Up @@ -16469,9 +16469,8 @@ AnnotationAssertion(terms:contributor obo:CL_0002260 <https://orcid.org/0000-000
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002260 "2010-09-08T02:29:38Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002260 "FMA:70547")
AnnotationAssertion(rdfs:label obo:CL_0002260 "epithelial cell of parathyroid gland")
EquivalentClasses(obo:CL_0002260 ObjectIntersectionOf(obo:CL_0002076 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001132)))
SubClassOf(obo:CL_0002260 obo:CL_0000150)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002260 obo:CL_0002076)
EquivalentClasses(obo:CL_0002260 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001132)))
SubClassOf(obo:CL_0002260 obo:CL_0002076)

# Class: obo:CL_0002261 (endothelial cell of viscerocranial mucosa)

Expand Down Expand Up @@ -20413,13 +20412,12 @@ SubClassOf(obo:CL_0002655 obo:CL_0002252)

# Class: obo:CL_0002656 (glandular cell of endometrium)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002656 "A glandular epithelial cell of the endometrium.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:25023676") obo:IAO_0000115 obo:CL_0002656 "A glandular epithelial cell of the endometrium. Following ovulation, these cells secrete a glycogen-rich substance known as histotroph or uterine milk, which nourishes the embryo if implantation occurs.")
AnnotationAssertion(terms:contributor obo:CL_0002656 <https://orcid.org/0000-0003-1980-3228>)
AnnotationAssertion(oboInOwl:creation_date obo:CL_0002656 "2011-07-08T03:54:08Z"^^xsd:dateTime)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002656 "FMA:86489")
AnnotationAssertion(rdfs:label obo:CL_0002656 "glandular cell of endometrium")
EquivalentClasses(obo:CL_0002656 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004811)))
SubClassOf(obo:CL_0002656 obo:CL_0000150)
EquivalentClasses(obo:CL_0002656 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002451) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032940)))

# Class: obo:CL_0002657 (glandular cell of esophagus)

Expand Down Expand Up @@ -27955,15 +27953,16 @@ AnnotationAssertion(rdfs:label obo:CL_1001586 "mammary gland glandular cell")
EquivalentClasses(obo:CL_1001586 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001911)))
SubClassOf(obo:CL_1001586 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003244))

# Class: obo:CL_1001587 (uterine cervix glandular cell)
# Class: obo:CL_1001587 (uterine cervix secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001587 "Glandular cell of uterine cervix epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001587 "CALOHA:TS-1273")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1273") oboInOwl:hasRelatedSynonym obo:CL_1001587 "cervix glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1273") oboInOwl:hasRelatedSynonym obo:CL_1001587 "cervix, uterine glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1273") oboInOwl:hasRelatedSynonym obo:CL_1001587 "cervix, uterine glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001587 "uterine cervix glandular cell")
EquivalentClasses(obo:CL_1001587 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000002)))
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1001587 "uterine cervix glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001587 "uterine cervix secretory cell")
EquivalentClasses(obo:CL_1001587 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000002)))
SubClassOf(obo:CL_1001587 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004801))

# Class: obo:CL_1001588 (colon glandular cell)
Expand All @@ -27975,34 +27974,35 @@ AnnotationAssertion(rdfs:label obo:CL_1001588 "colon glandular cell")
EquivalentClasses(obo:CL_1001588 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001155)))
SubClassOf(obo:CL_1001588 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000397))

# Class: obo:CL_1001589 (duodenum glandular cell)
# Class: obo:CL_1001589 (duodenum secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001589 "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001589 "CALOHA:TS-1275")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1275") oboInOwl:hasRelatedSynonym obo:CL_1001589 "duodenum glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001589 "duodenum glandular cell")
EquivalentClasses(obo:CL_1001589 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002114)))
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1275") oboInOwl:hasNarrowSynonym obo:CL_1001589 "duodenum glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001589 "duodenum secretory cell")
EquivalentClasses(obo:CL_1001589 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002114)))
SubClassOf(obo:CL_1001589 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0008346))

# Class: obo:CL_1001590 (epididymis glandular cell)
# Class: obo:CL_1001590 (epididymis secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001590 "Glandular cell of epididymal epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001590 "CALOHA:TS-1276")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1276") oboInOwl:hasRelatedSynonym obo:CL_1001590 "epididymal glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1276") oboInOwl:hasRelatedSynonym obo:CL_1001590 "epididymis glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001590 "epididymis glandular cell")
EquivalentClasses(obo:CL_1001590 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001301)))
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1276") oboInOwl:hasRelatedSynonym obo:CL_1001590 "epididymis glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001590 "epididymis secretory cell")
EquivalentClasses(obo:CL_1001590 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001301)))
SubClassOf(obo:CL_1001590 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004544))

# Class: obo:CL_1001591 (oviduct glandular cell)
# Class: obo:CL_1001591 (oviduct secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001591 "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001591 "CALOHA:TS-1277")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "fallopian tube glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "fallopian tube glandular cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "uterine tube glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001591 "oviduct glandular cell")
EquivalentClasses(obo:CL_1001591 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000993)))
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1001591 "oviduct glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001591 "oviduct secretory cell")
EquivalentClasses(obo:CL_1001591 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000993)))
SubClassOf(obo:CL_1001591 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004804))

# Class: obo:CL_1001592 (gallbladder glandular cell)
Expand All @@ -28018,13 +28018,12 @@ SubClassOf(obo:CL_1001592 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000202

# Class: obo:CL_1001593 (parathyroid glandular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001593 "Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001593 "Glandular (secretory) cell of parathyroid epithelium.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001593 "CALOHA:TS-1279")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1279") oboInOwl:hasRelatedSynonym obo:CL_1001593 "parathyroid gland glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1279") oboInOwl:hasRelatedSynonym obo:CL_1001593 "parathyroid gland glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001593 "parathyroid glandular cell")
EquivalentClasses(obo:CL_1001593 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001132)))
SubClassOf(obo:CL_1001593 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0011197))

# Class: obo:CL_1001595 (rectum glandular cell)

Expand Down Expand Up @@ -28055,16 +28054,16 @@ AnnotationAssertion(rdfs:label obo:CL_1001597 "seminal vesicle glandular cell")
EquivalentClasses(obo:CL_1001597 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000998)))
SubClassOf(obo:CL_1001597 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004805))

# Class: obo:CL_1001598 (small intestine glandular cell)
# Class: obo:CL_1001598 (small intestine secretory cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "NCI_Thesaurus:Small_Intestinal_Glandular_Cell") Annotation(oboInOwl:hasDbXref "NPX:PDR") obo:IAO_0000115 obo:CL_1001598 "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) .")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001598 "CALOHA:TS-1286")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001598 "FMA:86928")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1286") oboInOwl:hasNarrowSynonym obo:CL_1001598 "small intestinal glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1286") oboInOwl:hasRelatedSynonym obo:CL_1001598 "small bowel glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1286") oboInOwl:hasRelatedSynonym obo:CL_1001598 "small intestinal glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1286") oboInOwl:hasRelatedSynonym obo:CL_1001598 "small intestine glandular cells")
AnnotationAssertion(rdfs:label obo:CL_1001598 "small intestine glandular cell")
EquivalentClasses(obo:CL_1001598 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
AnnotationAssertion(rdfs:label obo:CL_1001598 "small intestine secretory cell")
EquivalentClasses(obo:CL_1001598 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002108)))
SubClassOf(obo:CL_1001598 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001902))

# Class: obo:CL_1001599 (pancreas exocrine glandular cell)
Expand Down Expand Up @@ -28154,6 +28153,14 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-2359") oboInOwl:has
AnnotationAssertion(rdfs:label obo:CL_1001611 "cerebellar neuron")
EquivalentClasses(obo:CL_1001611 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0002037)))

# Class: obo:CL_1100001 (secretory epithelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref <https://orcid.org/0000-0002-7073-9172>) obo:IAO_0000115 obo:CL_1100001 "An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules.")
AnnotationAssertion(terms:contributor obo:CL_1100001 <https://orcid.org/0000-0002-7073-9172>)
AnnotationAssertion(terms:date obo:CL_1100001 "2024-07-21T09:24:44Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_1100001 "secretory epithelial cell"@en)
EquivalentClasses(obo:CL_1100001 ObjectIntersectionOf(obo:CL_0000066 obo:CL_0000151))

# Class: obo:CL_2000000 (epidermal melanocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:TermGenie") obo:IAO_0000115 obo:CL_2000000 "Any melanocyte that is part of a epidermis.")
Expand Down

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