Merge pull request #683 from obophenotype/issue-663

add new term CL_0011025 (exhausted T cell)
obophenotype · May 20, 2020 · a1b0e84 · a1b0e84
2 parents 0a3db9b + a9f2102
commit a1b0e84
Showing 1 changed file with 10 additions and 0 deletions.
diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl
@@ -1894,6 +1894,7 @@ Declaration(Class(obo:CL_0011021))
 Declaration(Class(obo:CL_0011022))
 Declaration(Class(obo:CL_0011023))
 Declaration(Class(obo:CL_0011024))
+Declaration(Class(obo:CL_0011025))
 Declaration(Class(obo:CL_0011100))
 Declaration(Class(obo:CL_0011101))
 Declaration(Class(obo:CL_0011102))
@@ -22114,6 +22115,7 @@ AnnotationAssertion(rdfs:label obo:CL_0011023 "CD25+ mast cell")
 EquivalentClasses(obo:CL_0011023 ObjectIntersectionOf(obo:CL_0001063 ObjectSomeValuesFrom(obo:RO_0001000 obo:CL_0000097) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380)))
 SubClassOf(obo:CL_0011023 obo:CL_0001063)
 
+
 # Class: obo:CL_0011024 (double negative T regulatory cell)
 
 AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16285891") obo:IAO_0000115 obo:CL_0011024 "A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation.")
@@ -22125,6 +22127,14 @@ AnnotationAssertion(rdfs:label obo:CL_0011024 "double negative T regulatory cell
 EquivalentClasses(obo:CL_0011024 ObjectIntersectionOf(obo:CL_0002489 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777)))
 SubClassOf(obo:CL_0011024 obo:CL_0002489)
 
+# Class: obo:CL_0011025 (exhausted T cell)
+
+AnnotationAssertion(oboInOwl:created_by obo:CL_0011025 <http://orcid.org/0000-0001-5208-3432>)
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:26544946") oboInOwl:hasExactSynonym obo:CL_0011025 "An effector T cell that displays impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity) and has limited proliferative potential.")
+AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0011025 "Tex cell")
+AnnotationAssertion(rdfs:label obo:CL_0011025 "exhausted T cell")
+SubClassOf(obo:CL_0011025 obo:CL_0000911)
+
 # Class: obo:CL_0011100 (galanergic neuron)
 
 AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:NV") Annotation(oboInOwl:hasDbXref "PMID:23159249") Annotation(oboInOwl:hasDbXref "ZFIN:CVS") Annotation(oboInOwl:hasDbXref "ZFIN:YB") obo:IAO_0000115 obo:CL_0011100 "Neuron that secretes the neurotransmitter galanin.")