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Text def Purkinje neuron #2438

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Jul 18, 2024
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Text def Purkinje neuron #2438

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Text def Purkinje neuron
AvolaAmg Jul 17, 2024
f796e0a
Update cl-edit.owl
AvolaAmg Jul 18, 2024
2eaf86a
Merge branch 'master' into Text-def-Purkinje-neuron
AvolaAmg Jul 18, 2024
10dd27a
Update cl-edit.owl
AvolaAmg Jul 18, 2024
398239d
Merge branch 'Text-def-Purkinje-neuron' of https://github.com/obophen…
AvolaAmg Jul 18, 2024
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11 changes: 6 additions & 5 deletions src/ontology/cl-edit.owl
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Expand Up @@ -4622,14 +4622,15 @@ SubClassOf(obo:CL_0000120 obo:CL_0000117)

# Class: obo:CL_0000121 (Purkinje cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D011689") obo:IAO_0000115 obo:CL_0000121 "The output neuron of the cerebellar cortex.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D011689") Annotation(oboInOwl:hasDbXref "PMID:12907269") Annotation(oboInOwl:hasDbXref "PMID:14568361") Annotation(oboInOwl:hasDbXref "PMID:31424738") Annotation(oboInOwl:hasDbXref "PMID:33288911") Annotation(oboInOwl:hasDbXref "PMID:38168772") obo:IAO_0000115 obo:CL_0000121 "An inhibitory neuron and the sole output neuron of the cerebellar cortex, the Purkinje cell's soma is located between the granular and molecular layers of the cerebellum. It is one of the largest neural cells in the mammalian brain, ranging from 50 to 80 micrometers in diameter. A Purkinje cell presents planar, fan-shaped dendrites that branch extensively with little overlap. This cell receives synaptic input from parallel fibers, which modulate high-frequency spike activity known as \"simple spikes,\" and climbing fibers, which modulate infrequent calcium spike activity known as \"complex spikes\". Purkinje cells are involved in motor coordination, particularly in correcting movements in progress.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "BTO:0001011")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "CALOHA:TS-0845")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000121 "FMA:67969")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "Purkinje neuron")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "Purkinje's cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "cerebellar Purkinje cell")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000121 "cerebellum Purkinje cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28821816") oboInOwl:hasExactSynonym obo:CL_0000121 "Purkinje neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.proghi.2004.07.002") oboInOwl:hasExactSynonym obo:CL_0000121 "cerebellar Purkinje cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38168772") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_0000121 "PC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28821816") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_0000121 "PN")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17535929") Annotation(oboInOwl:hasDbXref "PMID:27215193") Annotation(oboInOwl:hasDbXref "PMID:37426070") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.stem.2023.11.013") rdfs:comment obo:CL_0000121 "Neurodegenerative disorders affecting Purkinje cells disrupt motor functions. Some of the neurodegenerative disorders that causes loss and degeration of Purkinje cells are Spinocerebellar ataxias (SCAs) (Josef P Kapfhammer and Etsuko Shimobayashi 2023), Friedreich's ataxia (FRDA) (Kevin C Kemp et al., 2016), Fetal alcohol syndrome (Laurent Servais et al., 2016), Dandy-Walker malformation (Alexander Atamian et al., 2024).")
AnnotationAssertion(rdfs:label obo:CL_0000121 "Purkinje cell")
SubClassOf(obo:CL_0000121 obo:CL_0000117)
SubClassOf(obo:CL_0000121 obo:CL_0000527)
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