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oscryan committed Mar 26, 2024
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<para id="fs-id2026183">In an X-linked cross, the genotypes of F<sub>1</sub> and F<sub>2</sub> offspring depend on whether the recessive trait was expressed by the male or the female in the P<sub>1</sub> generation. With regard to <emphasis effect="italics">Drosophila</emphasis> eye color, when the P<sub>1</sub> male expresses the white-eye phenotype and the female is homozygous red-eyed, all members of the F<sub>1</sub> generation exhibit red eyes (<link target-id="fig-ch12_02_10"/>). The F<sub>1</sub> females are heterozygous (X<emphasis effect="italics"><sup>W</sup></emphasis>X<emphasis effect="italics"><sup>w</sup></emphasis>), and the males are all X<emphasis effect="italics"><sup>W</sup></emphasis>Y, having received their X chromosome from the homozygous dominant P<sub>1</sub> female and their Y chromosome from the P<sub>1</sub> male. A subsequent cross between the X<emphasis effect="italics"><sup>W</sup></emphasis>X<emphasis effect="italics"><sup>w</sup></emphasis> female and the X<emphasis effect="italics"><sup>W</sup></emphasis>Y<emphasis effect="italics"/> male would produce only red-eyed females (with X<emphasis effect="italics"><sup>W</sup></emphasis>X<emphasis effect="italics"><sup>W</sup></emphasis> or X<emphasis effect="italics"><sup>W</sup></emphasis>X<emphasis effect="italics"><sup>w</sup></emphasis> genotypes) and both red- and white-eyed males (with X<emphasis effect="italics"><sup>W</sup></emphasis>Y<emphasis effect="italics"/> or X<emphasis effect="italics"><sup>w</sup></emphasis>Y<emphasis effect="italics"/> genotypes). Now, consider a cross between a homozygous white-eyed female and a male with red eyes. The F<sub>1</sub> generation would exhibit only heterozygous red-eyed females (X<emphasis effect="italics"><sup>W</sup></emphasis>X<emphasis effect="italics"><sup>w</sup></emphasis>) and only white-eyed males (X<emphasis effect="italics"><sup>w</sup></emphasis>Y). Half of the F<sub>2</sub> females would be red-eyed (X<emphasis effect="italics"><sup>W</sup></emphasis>X<emphasis effect="italics"><sup>w</sup></emphasis>) and half would be white-eyed (X<emphasis effect="italics"><sup>w</sup></emphasis>X<emphasis effect="italics"><sup>w</sup></emphasis>). Similarly, half of the F<sub>2</sub> males would be red-eyed (X<emphasis effect="italics"><sup>W</sup></emphasis>Y) and half would be white-eyed (X<emphasis effect="italics"><sup>w</sup></emphasis>Y).</para>
<note id="fs-idm112850592" class="visual-connection">
<para id="fs-id2955499">
<figure id="fig-ch12_02_10"><media id="fs-id2583976" alt="This illustration shows a Punnett square analysis of fruit fly eye color, which is a sex-linked trait. A red-eyed male fruit fly with the genotype X superscript w baseline, Y, is crossed with a white-eyed female fruit fly with the genotype X superscript w, X superscript w baseline. All of the female offspring acquire a dominant upper case W allele from the father and a recessive lower case w allele from the mother, and are therefore heterozygous dominant with red eye color. All of the male offspring acquire a recessive w allele from the mother and a Y chromosome from the father and are therefore hemizygous recessive with white eye color.">
<figure id="fig-ch12_02_10"><media id="fs-id2583976" alt="This illustration shows a Punnett square analysis of fruit fly eye color, which is a sex-linked trait. A red-eyed male fruit fly with the genotype X superscript upper case W baseline, Y, is crossed with a white-eyed female fruit fly with the genotype X superscript lower case w baseline, X superscript lower case w baseline. All of the female offspring acquire a dominant upper case W allele from the father and a recessive lower case w allele from the mother, and are therefore heterozygous dominant with red eye color. All of the male offspring acquire a recessive lower case w allele from the mother and a Y chromosome from the father and are therefore hemizygous recessive with white eye color.">
<image mime-type="image/jpg" src="../../media/Figure_12_02_09.jpg" width="400"/>
</media>

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