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include ld and finemapping parquet meta info
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mkarmona authored Feb 1, 2019
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Expand Up @@ -206,6 +206,24 @@ Todo:

Credible set analysis results used to link index variants to tag variants. Full finemapping methods can be seen here: https://github.com/opentargets/finemapping

##### Parquet meta info

```
file schema: schema
--------------------------------------------------------------------------------
study_id: OPTIONAL BINARY L:STRING R:0 D:1
lead_chrom: OPTIONAL BINARY L:STRING R:0 D:1
lead_pos: OPTIONAL INT64 R:0 D:1
lead_ref: OPTIONAL BINARY L:STRING R:0 D:1
lead_alt: OPTIONAL BINARY L:STRING R:0 D:1
tag_chrom: OPTIONAL BINARY L:STRING R:0 D:1
tag_pos: OPTIONAL INT64 R:0 D:1
tag_ref: OPTIONAL BINARY L:STRING R:0 D:1
tag_alt: OPTIONAL BINARY L:STRING R:0 D:1
log10_ABF: OPTIONAL DOUBLE R:0 D:1
posterior_prob: OPTIONAL DOUBLE R:0 D:1
```

##### Finemapping table columns
- `study_id`: unique identifier for study
- `index_variantid_b37`: unique variant identifier for index variant, chrom_pos_ref_alt (build 37)
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Table of LD values linking index varaints to tag variants.

##### Parquet meta info

```
file schema: schema
--------------------------------------------------------------------------------
study_id: OPTIONAL BINARY L:STRING R:0 D:1
lead_chrom: OPTIONAL BINARY L:STRING R:0 D:1
lead_pos: OPTIONAL INT64 R:0 D:1
lead_ref: OPTIONAL BINARY L:STRING R:0 D:1
lead_alt: OPTIONAL BINARY L:STRING R:0 D:1
tag_chrom: OPTIONAL BINARY L:STRING R:0 D:1
tag_pos: OPTIONAL INT64 R:0 D:1
tag_ref: OPTIONAL BINARY L:STRING R:0 D:1
tag_alt: OPTIONAL BINARY L:STRING R:0 D:1
overall_r2: OPTIONAL DOUBLE R:0 D:1
AFR_1000G_prop: OPTIONAL DOUBLE R:0 D:1
AMR_1000G_prop: OPTIONAL DOUBLE R:0 D:1
EAS_1000G_prop: OPTIONAL DOUBLE R:0 D:1
EUR_1000G_prop: OPTIONAL DOUBLE R:0 D:1
SAS_1000G_prop: OPTIONAL DOUBLE R:0 D:1
```

##### LD table columns
- `study_id`: unique identifier for study
- `index_variantid_b37`: unique variant identifier for index variant, chrom_pos_ref_alt (build 37)
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