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v1.2.0 - Platon uses UniProt clusters
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@oschwengers oschwengers released this 16 Apr 13:20
v1.2.0
dac7a1d

This is a major update on the latest release.

In this release we introduce UniProt's UniRef90 protein clusters which replaced the NCBI's PCLA prokaryote clusters. Furthermore, we substantially revised and improved the RDS formula of the RDS metric and added new contig characterizations. Also Platon now takes advantage of the manually curated relaxase HMM profiles of MacSyFinder.

In detail:

  • enhanced formula for the RDS calculation
  • enlarged MPS db size (~4.1 mio) due to a switch to UniProt's UniRef90 protein clusters
  • incorporation of MacSyFinder 's ralaxase HMM profiles
  • implementation of an oriT detection by incorporating MOB-suite 's oriT sequences
  • updates of all databaes
  • many tiny bug fixes and improvements

The current database is available at Zenodo: https://zenodo.org/record/3751774 10.5281/zenodo.3349651

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