Code accompanying Implications of TP53 Allelic State for Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Bernard E, Nannya Y, Hasserjian RP, et al., Nature Medicine, 26, 1549-1556, 2020.

📂 Repository Structure

• data/: the folder contains the clinical and molecular data necessary to reproduce the results of the study. See the README in the data/ folder for details about data structure.

• MDS-TP53-state.ipynb: the jupyter notebook with R code to reproduce results and figures.

• MDS-TP53-state.html: an html version of the notebook.

🚀 Getting started with this repository

Clone the repository

To clone this repository on your local computer please run:

$ git clone https://github.com/papaemmelab/MDS-TP53-state

R packages you need to install:

# run in an R console
install.packages('ggplot2',      repos = 'http://cran.us.r-project.org')
install.packages('reshape2',      repos = 'http://cran.us.r-project.org')
install.packages('survival',     repos = 'http://cran.us.r-project.org')
install.packages('survminer',    repos = 'http://cran.us.r-project.org')
install.packages('cmprsk',       repos = 'http://cran.us.r-project.org')
install.packages('stringr',      repos = 'http://cran.us.r-project.org')

❓ Question

If any question on the repo, feel free to contact Elsa.