My take on dynamic DNS using AWS Route 53. Features support for both IPV4 A records and IPV6 AAAA records. Works with Python 2.6+.
Setup your AWS credentials. There are many ways to do this, see: https://boto3.readthedocs.io/en/latest/guide/quickstart.html#configuration. The configured user must have Route 53 read & write access.
Install Python requirements:
$ pip install -r requirements.txt
At the top of the script there are two variables you must change, domain and subdomain.
You must already have the hosted zone setup in your AWS account that matches domain.
Run the script python dyndns53.py. It works best when run on a cron every hour.