Sikuli[1] is pretty awesome, but it requires java. Bleh.
This is a project to provide the same API using regular CPython libraries.
The goal is to be able to run any script which works in the Java IDE.
Installation:
$ git clone https://github.com/shish/sikulpy
$ cd sikulpy
$ python3.7 -m venv .env
$ . .env/bin/activate
$ pip install -e ./
$ sikulpy ~/Documents/sikuli/foo.sikuli
The parts of the Sikuli API that I'm personally using are fairly stable; I'm using it in production on Linux, with development on OSX and occasional testing on Windows.
Parts of the API which are known to be incomplete have tasks filed here: API Completion