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Markus Mittnenzweig committed May 21, 2024
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This repository is the accompanying code for our paper on the development of extraembryonic ectoderm and embryonic tissues during mouse gastrulation. There is an [MCView shiny app](https://tanaylab.weizmann.ac.il/EmbExe) where you can interrogate the data. The code is splitted into jupyter notebooks that can be found in the notebook folder.

### Quick links

- Interactive [extraembryonic ectoderm](https://tanaylab.weizmann.ac.il/EmbExe/ExE_ectoderm/) and [embryonic](https://tanaylab.weizmann.ac.il/EmbExe/embryonic_manifold/) atlases

- Metacells paper: Ben-Kiki et al. 2022 [Genome Biology](https://doi.org/10.1186/s13059-022-02667-1)

- [Metacells python package](https://github.com/tanaylab/metacells)

- [MCView] (https://github.com/tanaylab/MCView)

- Raw FASTQ files are available under GEO accessions [GSE267870](https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE267870)

## Running the notebooks

Prior to any analysis, after cloning the repository, please download first the necessary data by running (in the root directory of the cloned repository):
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17. wt_atlas_projection_of_exutero_embryos - atlas projection of ex utero data on WT atlas
18. atlas_self_projection_of_wt_cells

Contact

For help, please contact [email protected] or [email protected] .

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