CRISPR Guide RNA Designer
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Updated
Apr 3, 2022 - Python
CRISPR Guide RNA Designer
Pre-trained models for the crisprScore package
A guideRNA design tool for the modern era.
Bowtie-based alignment of CRISPR gRNA spacer sequences
BWA-based alignment of CRISPR gRNA spacer sequences
Collection of R packages that work in harmony for CRISPR gRNA design
⛓️ Automating construction of oligo library sequences for oligo array synthesis.
Fork of Azimuth (Machine Learning-Based Predictive Modelling of CRISPR/Cas9 guide efficiency), updated to work with Python 3.10+
CRISPR, faster, better – The Crackling method for whole-genome target detection
Shiny interface for CRISPR gRNAs designed with the crisprVerse
Visualization of CRISPR guide RNAs (gRNAs)
A gRNA database generation tool.
ALLEGRO: An Algorithm Leveraging Linear Programing to Enhance Guide RNA Optimization
Creates a construct developed by the Niles Lab at MIT, designed to deliver a 3' UTR post-transcriptional regulatory element payload to a specific given gene in Plasmodium falciparum.
Comprehensive design of CRISPR gRNAs for nucleases and base editors
Useful human and mouse data for the crisprVerse ecosystem
Base functions and classes for CRISPR gRNA design
A Snakemake workflow for the design of small guide RNAs (sgRNAs) for CRISPR applications.
Tutorials for the crisprVerse
On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
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