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225 public repositories
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The physiologically-based whole-body model of the glucose-insulin-glucagon regulatory system
Updated
Mar 23, 2019
MATLAB
Physiologically Based Pharmacokinetic Models for Pregnant Women
Implementation of inhalation model in MoBi
Implementation of Dancik et al (2013) skin permeation model in MoBi
Whole-body PBPK model of digoxin as P-gp DDI victim drug
Whole-body PBPK model of Vancomycin
Updated
Oct 14, 2021
MATLAB
A Quantitative Systems Pharmacology kidney model of diabetes associated renal hyperfiltration and the effects of SGLT inhibitors.
Whole-body PBPK model of voriconazole as CYP2C19 substrate and CYP3A4 perpetrator drug
Physiology-based systems pharmacology model of thyroid hormones regulation in rat and human
Pulmonary drug absorption implemented in MoBi (Eriksson et al. 2020)
Modeling of published clinical Itraconazole-Digoxin-DDI studies for model evaluation
Whole-body PBPK model of Irinotecan (CPT-11) & SN-38 determining tumor tissue kinetics of both parent drug & active metabolite.
Whole-body PBPK model of theophylline as CYP1A2 DDI victim drug
Modeling of published clinical Cimetidine-Carbamazepine DDI studies for model evaluation
Whole-body PBPK model of midazolam as CYP3A4 DDI victim drug
Updated
Jul 7, 2022
MATLAB
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