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# shovill | ||
Faster SPAdes assembly of Illumina reads | ||
# Shovill | ||
Faster smarter SPAdes assembly of Illumina reads | ||
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## Introduction | ||
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The SPAdes genome assembler has become the *de facto* standard *de novo* genome assembler | ||
for Illumina whole genome sequencing data of bacteria and other small microbes. SPAdes | ||
was a major improvement over previous assemblers like Velvet, but it can be very slow to run | ||
and does not handle overlapping paired-end reads well. | ||
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Shovill is a pipeline which uses SPAdes at its core, but alters the steps before and after | ||
the primary assembly step to get near-identical results in far less time. | ||
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## Main steps | ||
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1. Correct reads conservatively | ||
2. Pre-overlap paired-end reads | ||
3. Assemble with "vanilla" SPAdes with modified kmer range | ||
4. Correct minor assembly errors (optional) | ||
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## Installation | ||
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### Source | ||
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``` | ||
git clone https://github.com/tseemann/shovill.git | ||
./shovill/shovill -h | ||
``` | ||
You will need to install all the dependencies manually: | ||
* SPAdes | ||
* Lighter | ||
* FLASH | ||
* SAMtools | ||
* BWA MEM | ||
* PILON | ||
* KmerStream | ||
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### Homebrew | ||
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**NOT READY YET** | ||
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``` | ||
brew tap homebrew/science | ||
brew tap tseemann/bioinformatics-linux | ||
brew install shovill | ||
``` | ||
Using Homebrew will install all the dependencies for you. | ||
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## Feedback | ||
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Please file questions, bugs or ideas to the [Issue Tracker](https://github.com/tseemann/shovill/issues) | ||
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## License | ||
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[GPLv3](https://raw.githubusercontent.com/tseemann/shovill/master/LICENSE) | ||
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## Citation | ||
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Not published yet. | ||
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## Authors | ||
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* Torsten Seemann | ||
* Jason Kwong | ||
* Anders Goncalves da Silva | ||
* Mark Schultz | ||
* Dieter Bulach | ||
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