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Release notes v20230831

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@OHDSIVocabularyReleaseRobot OHDSIVocabularyReleaseRobot released this 31 Aug 21:59
· 590 commits to master since this release
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This guide can provide you more background on how to read the release notes.

What's New

1. CPT4

  • The vocabulary was updated according to the 2023AA version of the UMLS source.
  • 1612 CPT4 concepts in Procedure, Measurement and Observation domains were mapped to standard concepts in the respective domains, and 2761 concepts were embedded into the hierarchy of SNOMED.
  • Equivalence relationships between CPT4 and SNOMED ( 'CPT4 - SNOMED cat' and 'CPT4 - SNOMED eq') are created using the inter-vocabulary synonymous and categorical relationships present in the UMLS source, respectively. In the scope of this release, 2163 such links were added. Upon addition a new target concept to the UMLS source we deprecate the previous link of equivalence for the respective CPT4 concept.
  • Concepts whose domains had been changed to Visit in the course of v20230116_major release obtained their original domains (Observation, Procedure, Measurement) as per community request.
  • In CPT4 concepts migrate between categories and obtain new concept_codes. This results in semantic duplicates within the vocabulary. 71 duplicative concepts were destandardized and mapped over to the newest CPT4 codes or the standard SNOMED concepts in the respective domain.
  • 10 CPT4 Hierarchy concepts for COVID-19 vaccines were mapped to standard concepts in the Drug domain according to their semantics.
  • Logic of concept class assignment to CPT4 Modifiers was fixed, so that deprecated by the source modifiers preserve their concept_class_id = ‘CPT4 Modifier’.

2. RxNorm

  • The vocabulary has been updated to July 2023 version

3. NDC/SPL

  • The vocabulary has been updated to August 2023 version, effective from 27th of August

4. LOINC

  • LOINC vocabulary has been updated with its 2.75 Aug 2023 version.

  • LOINC-SNOMED hierarchy was improved:

    Some LOINC concepts had multiple ancestors in SNOMED, which were ancestors and descendants of each other. This resulted in loops of hierarchical relationships

  • COVID-2019-related lab tests were rolled up to the respective parent concept and were included in the hierarchy of Measurement of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

  • One-to-many mapping was fixed.

5. VANDF

  • In this release, we refresh VANDF and VA Class vocabularies - Veterans Health Administration National Drug File, one of drug source vocabularies.
  • We changed the logic of the domain assignment. Previously, all of the concepts within VANDF vocabulary were considered Drugs, even though they did not qualify as Drugs in OHDSI. Currently, we use hierarchical relationships with VA Class vocabulary to assign Device domain correctly.

6. Co-connect

  • Co-connect family of vocabularies are now distributed under the open-source license.
  • Reference changed to authoring institution.

7. Smoking hierarchy (UK Biobank, HCPCS, ICD10CM)

  • During this release we continued remapping Smoking related concepts in source vocabularies (UK Biobank, HCPCS, ICD10CM).
  • Minor bugfixing included into the release of the affected vocabularies.

Find more information about the Smoking hierarchy convention here.

8. Read

  • Enhanced and refined vaccines mapping.
  • Successfully incorporated smoking mapping according to the Smoking Convention.
  • Resolved improper one-to-many mappings, including instances where concepts were both ascendants and descendants of each other.

9. Community contribution

As a part of Vocabularies improvement initiative, August release was the first release in which we implemented community contribution as a transparent pathway for community to contribute their vocabularies and suggest changes to the existing.

We incorporated all submissions submitted and approved (if modification of content) by the end of June (2 months before the release).

These include:

  1. New vocabularies - NHS Ethnic category and NHS Place of Service (link)
  2. Remapping of ICD10CM terms to SNOMED (link)
  3. Addition of new RxNorm Extension terms to support analytics across data sources using Z index (link)

More details about the process can be found here and here.

10. Problems found during the release, but not yet fixed

  • Nearly 30% of VANDF mappings, related to solutions of all kinds (topical solution, injectable solution, etc.) are incorrect. These mappings are coming directly from the source data. VANDF and target RxNorm concepts differ in the amount of ingredients and concentration of the ingredients. We have found no differences in ingredients between VANDF and RxNorm concepts. Therefore, mappings may be used for the drug_exposure population, unless drug dosages are a prime question of the study. The examples of the mappings may be found at Known Issues page

  • The CPT Editorial Panel approves new Vaccine and Immunization codes and releases them to the AMA website quarterly or sometimes even monthly. These changes often are not captured by our releases of CPT4 OMOP vocabulary, as we take UMLS as a source, and it’s updated bi-annually. Besides, the newly introduced stable cadence of bi-annual OHDSI Vocabulary releases limits our ability to add codes on requests. It may pose a problem for CDM users, who need these codes for their research.
    The Vocabulary Team usually includes such concepts in the nearest scheduled CPT4 release (see Roadmap) on request. We recommend adding the necessary codes to the local CDMs in case of urgent need.

Domain changes

vocabulary_idold_domain_idnew_domain_idcount
CPT4DrugMeasurement1
CPT4MeasurementObservation24
CPT4MeasurementProcedure2
CPT4ProcedureMeasurement5
CPT4ProcedureObservation17
CPT4ProviderObservation9
CPT4VisitMeasurement3
CPT4VisitObservation175
CPT4VisitProcedure8
HCPCSVisitObservation16
LOINCMeasurementObservation2
LOINCObservationNote1
VANDFDrugDevice11598

Newly added concepts grouped by Vocabulary_id and Domain

vocabulary_iddomain_idcount
CPT4Drug1
CPT4Measurement83
CPT4Observation23
CPT4Procedure142
LOINCMeasurement2453
LOINCMeas Value215
LOINCNote114
LOINCObservation1217
LOINCProcedure402
NDCDevice80
NDCDrug15352
NHS Ethnic CategoryRace15
NHS Place of ServiceVisit15
RxNormDrug663
RxNorm ExtensionDrug2215
SPLDevice3
SPLDrug15242
VANDFDevice736
VANDFDrug813

Standard concept changes

vocabulary_idold_standard_conceptnew_standard_conceptcount
CPT4StandardNon-standard with mapping1617
CPT4Non-standard with mappingStandard3
LOINCStandardNon-standard with mapping1015
LOINCClassification without mappingNon-standard without mapping59
LOINCStandardNon-standard without mapping12
LOINCNon-standard with mappingStandard1
RxNormStandardNon-standard without mapping49
RxNormStandardNon-standard with mapping7
RxNormClassification without mappingNon-standard without mapping2
RxNorm ExtensionStandardNon-standard with mapping1410
SPLClassification without mappingNon-standard without mapping3
SPLClassification without mappingNon-standard with mapping1
VANDFNon-standard without mappingStandard9565
VANDFNon-standard with mappingStandard10

Newly added concepts and their standard concept status

vocabulary_idnew_standard_conceptcount
CPT4Classification with mapping6
CPT4Non-standard with mapping9
CPT4Classification without mapping40
CPT4Standard194
LOINCNon-standard with mapping1
LOINCClassification without mapping620
LOINCNon-standard without mapping1033
LOINCStandard2747
NDCStandard80
NDCNon-standard with mapping7026
NDCNon-standard without mapping8326
NHS Ethnic CategoryNon-standard with mapping15
NHS Place of ServiceNon-standard with mapping15
RxNormNon-standard with mapping28
RxNormNon-standard without mapping33
RxNormClassification without mapping82
RxNormStandard520
RxNorm ExtensionNon-standard without mapping79
RxNorm ExtensionStandard2136
SPLClassification without mapping15245
VANDFNon-standard without mapping217
VANDFNon-standard with mapping617
VANDFStandard715
VocabularyNon-standard without mapping2

Changes of concept mapping status grouped by target domain

vocabulary_idOld target Domain/StatusNew target Domain/Statuscount
AMTDrugNo mapping1
ATCDrugNo mapping1
ATCNo mappingDrug2
CPT4Drug/ProcedureDrug3
CPT4MeasurementProcedure7
CPT4New conceptDrug7
CPT4New conceptMeasurement78
CPT4New conceptObservation9
CPT4New conceptProcedure115
CPT4No mappingDrug4
CPT4ObservationCondition5
CPT4ObservationMeasurement1
CPT4ObservationProcedure1
CPT4ProcedureMeasurement16
CPT4ProcedureObservation7
CPT4ProcedureObservation/Procedure1
CPT4ProviderObservation3
CPT4ProviderProcedure6
CPT4VisitObservation1
CTDDrugNo mapping1
DA_FranceDrugNo mapping2
dm+dDrugNo mapping12
GCN_SEQNODrugNo mapping2
GPIDrugNo mapping7
GRRDrugNo mapping2
HCPCSNo mappingObservation1
HemOncDrugNo mapping1
ICD10CMConditionCondition/Observation18
ICD10CMNo mappingCondition/Observation1
ICD10CMNo mappingObservation4
JMDCDrugNo mapping1
LOINCMeasurementObservation1
LOINCMeas ValueNo mapping12
LOINCNew conceptMeasurement1950
LOINCNew conceptMeas Value215
LOINCNew conceptNote94
LOINCNew conceptObservation172
LOINCNew conceptProcedure317
LOINCObservationNote1
NCCDDrugNo mapping1
NCCDNo mappingDrug1
NDCDrugNo mapping175
NDCNew conceptDevice80
NDCNew conceptDrug7026
NDCNo mappingDrug1737
NHS Ethnic CategoryNew conceptRace15
NHS Place of ServiceNew conceptVisit15
OMOP Invest DrugDrugNo mapping21
OPSProcedureNo mapping4
ReadDrugDrug/Procedure126
ReadDrugNo mapping4
ReadDrug/ObservationDrug2
ReadDrug/ProcedureProcedure2
ReadNo mappingCondition1
ReadNo mappingDrug6
ReadNo mappingDrug/Procedure9
ReadNo mappingMeasurement1
ReadNo mappingObservation69
ReadProvider/VisitVisit1
ReadRaceNo mapping3
ReadVisitNo mapping1
RxNormDrugNo mapping49
RxNormNew conceptDrug548
RxNorm ExtensionNew conceptDrug2136
SNOMEDNo mappingDrug6
SNOMEDObservationDrug/Observation1
SPLNo mappingDrug1
UK BiobankNo mappingObservation164
UK BiobankNo mappingProvider10
VANDFDrugDevice10
VANDFNew conceptDevice715
VANDFNew conceptDrug617
VANDFNo mappingDevice9565
VANDFNo mappingDrug86

New vocabularies added

vocabulary_id
NHS Ethnic Category
NHS Place of Service

New vocabulary dependencies

source vocabulary_idtarget vocabulary_idcount
NHS Ethnic CategoryRace15
NHS Place of ServiceCMS Place of Service9
NHS Place of ServiceNUCC6

If you have any questions, please try to find the answers on http://forums.ohdsi.org. If you can't find it, please ask here: http://forums.ohdsi.org/t/vocabulary-release-questions/6650