Skip to content

Commit

Permalink
SPELLING: spelling::spell_check_package() fixes
Browse files Browse the repository at this point in the history
  • Loading branch information
HenrikBengtsson committed Oct 6, 2021
1 parent 1644a34 commit bb67aaf
Show file tree
Hide file tree
Showing 2 changed files with 88 additions and 4 deletions.
84 changes: 84 additions & 0 deletions inst/WORDLIST
Original file line number Diff line number Diff line change
@@ -0,0 +1,84 @@
Allelic
Beraldi
Biostatistics
CGHub
CN
ChrX
Fof
GC
Pre
README
Studer
TCGA
VE
Venkat
WGS
allelic
aneuploidy
autosomes
bam
bp
catalogued
clusteredcncf
cn
cncf
cnlr
codecov
csv
cval
dbSNP
dipLogR
emcncf
exome
exomes
extcode
extdata
findDiploidLogR
gbuild
germline
gz
hashmark
het
heterozygote
heterozygotes
heterozygous
hets
hetscale
hg
io
jointseg
kb
kth
lcn
loess
logOR
logR
macOS
mafR
mpileup
mskcc
nbhd
ndepth
nfrac
nhet
normalbam
outputfile
pctGCdata
perl
ploidy
polyclonal
pre
preProcSample
procSample
samtools
seg
seshanv
shenr
snp
snps
subclonal
tcn
tumorbam
udef
vaf
vcffile
8 changes: 4 additions & 4 deletions vignettes/FACETS.Rnw
Original file line number Diff line number Diff line change
Expand Up @@ -90,7 +90,7 @@ library(facets)

\noindent
We first perform various pre-processing steps to prepare the data for
segmenation analysis. Positions with total read count below a lower depth
segmentation analysis. Positions with total read count below a lower depth
threshold (default 35, use ndepth to change the default value) or exceed an
upper threshold (> 1000) (excessive coverage) in the matched normal sample were
removed. We scan all positions by 150-250 bp interval to space out SNP-dense
Expand Down Expand Up @@ -119,8 +119,8 @@ xx = preProcSample(rcmat)

\noindent
A bivariate genome segmentation is performed on logR and logOR by extending the
CBS algotithm \citep{olshen04,venkat07} to the bivariate scenario using a $T^2$
statistic for identifiying change points. If the maximal statistic is greater
CBS algorithm \citep{olshen04,venkat07} to the bivariate scenario using a $T^2$
statistic for identifying change points. If the maximal statistic is greater
than a pre-determined critical value (cval), we declare a change exists and the
change points that maximize this statistic. Lower cval lead to higher
sensitivity for small changes. After segmentation, a clustering process is
Expand Down Expand Up @@ -208,7 +208,7 @@ plotSample(x=oo,emfit=fit)
The top panel of the figure displays logR with chromosomes alternating in blue
and gray. The green line indicates the median logR in the sample. The purple
line indicates the logR of the diploid state. The second panel displays
logOR. Segment means are ploted in red lines. The third panel plots the total
logOR. Segment means are plotted in red lines. The third panel plots the total
(black) and minor (red) copy number for each segment. The bottom bar shows the
associated cellular fraction (cf). Dark blue indicates high cf. Light blue
indicates low cf. Beige indicates a normal segment (total=2,minor=1).
Expand Down

0 comments on commit bb67aaf

Please sign in to comment.