Skip to content

Commit

Permalink
Fixes #2240 NTR lipid associated macrophage
Browse files Browse the repository at this point in the history 
Fixes #2240 NTR lipid associated macrophage
  • Loading branch information
@aleixpuigb
aleixpuigb committed Oct 17, 2024
1 parent 707a393 commit a29c784
Show file tree
Hide file tree
Showing 2 changed files with 17 additions and 4 deletions.
20 changes: 16 additions & 4 deletions src/ontology/cl-edit.owl
View file
Original file line number Diff line number Diff line change
Expand Up @@ -3038,6 +3038,7 @@ Declaration(Class(obo:CL_4033066))
Declaration(Class(obo:CL_4033067))
Declaration(Class(obo:CL_4033083))
Declaration(Class(obo:CL_4033084))
Declaration(Class(obo:CL_4033086))
Declaration(Class(obo:CL_4040000))
Declaration(Class(obo:CL_4040001))
Declaration(Class(obo:CL_4040002))
Expand Down Expand Up @@ -3331,7 +3332,7 @@ AnnotationAssertion(rdfs:label obo:IAO_0000115 "definition")

AnnotationAssertion(rdfs:label obo:IAO_0000424 "expand expression to")

# Annotation Property: obo:IAO_0000700 (preferred_root)
# Annotation Property: obo:IAO_0000700 (has ontology root term)

AnnotationAssertion(rdfs:label obo:IAO_0000700 "preferred_root")

Expand Down Expand Up @@ -3425,11 +3426,11 @@ AnnotationAssertion(rdfs:label oboInOwl:hasBroadSynonym "has_broad_synonym")

AnnotationAssertion(rdfs:label oboInOwl:hasDbXref "database_cross_reference")

# Annotation Property: oboInOwl:hasExactSynonym (has_exact_synonym)
# Annotation Property: oboInOwl:hasExactSynonym (has exact synonym)

AnnotationAssertion(rdfs:label oboInOwl:hasExactSynonym "has_exact_synonym")

# Annotation Property: oboInOwl:hasNarrowSynonym (has_narrow_synonym)
# Annotation Property: oboInOwl:hasNarrowSynonym (has narrow synonym)

AnnotationAssertion(rdfs:label oboInOwl:hasNarrowSynonym "has_narrow_synonym")

Expand Down Expand Up @@ -27999,8 +28000,8 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "HPA:HPA") Annotation(oboInOwl
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001591 "CALOHA:TS-1277")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "fallopian tube glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "fallopian tube glandular cells")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "uterine tube glandular cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_1001591 "oviduct glandular cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1277") oboInOwl:hasRelatedSynonym obo:CL_1001591 "uterine tube glandular cell")
AnnotationAssertion(rdfs:label obo:CL_1001591 "oviduct secretory cell")
EquivalentClasses(obo:CL_1001591 ObjectIntersectionOf(obo:CL_1100001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000993)))
SubClassOf(obo:CL_1001591 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004804))
Expand Down Expand Up @@ -32133,6 +32134,17 @@ SubClassOf(obo:CL_4033084 obo:CL_0000501)
SubClassOf(obo:CL_4033084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001305))
SubClassOf(obo:CL_4033084 ObjectSomeValuesFrom(obo:RO_0002207 obo:CL_4033083))

# Class: obo:CL_4033086 (lipid-associated macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31257031") Annotation(oboInOwl:hasDbXref "PMID:34876704") Annotation(oboInOwl:hasDbXref "PMID:35712121") obo:IAO_0000115 obo:CL_4033086 "A tissue-resident macrophage that is associated with lipids. This cell responsible of anti-inflammatory functions, lipid accumulation and enhancing phagocytosis (Wculek et al., 2022, Liu et al., 2022). In mice and humans, a lipid-associated macrophage is characterized by the marker Trem2 (Jaitlin et al., 2019).")
AnnotationAssertion(terms:contributor obo:CL_4033086 <https://orcid.org/0000-0001-6677-8489>)
AnnotationAssertion(terms:contributor obo:CL_4033086 <https://orcid.org/0000-0001-8134-3037>)
AnnotationAssertion(terms:date obo:CL_4033086 "2024-10-17T10:20:13Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31257031") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4033086 "LAM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35021063") Annotation(oboInOwl:hasDbXref "PMID:37153549") rdfs:comment obo:CL_4033086 "Distinct from “adipose macrophage” in Trem2 expression, and is not limited to adipose tissue. Guilliams et al. describe these cells as being distinct from Kupffer cells.")
AnnotationAssertion(rdfs:label obo:CL_4033086 "lipid-associated macrophage")
SubClassOf(obo:CL_4033086 obo:CL_0000235)

# Class: obo:CL_4040000 (glial restricted tripotential precursor cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10719353") obo:IAO_0000115 obo:CL_4040000 "A glial precursor cell that generates oligodendrocytes and type-1 and type-2 astrocytes. It has been shown in some mammals that this cell type may express A2B5, nestin, FGFR-1, FGFR-2, FGFR-3, PLP, and DM-20 antigens. Unlike oligodendrocyte precursor cell, it does not initially express PDGFR-alpha and can differentiate into both type-1 and type-2 astrocytes.")
Expand Down
1 change: 1 addition & 0 deletions src/ontology/imports/pr_terms.txt
View file
Original file line number Diff line number Diff line change
Expand Up @@ -46,3 +46,4 @@ PR:000014898
PR:000007643
PR:000004691
PR:000013047
PR:000016626

0 comments on commit a29c784

Please sign in to comment.