Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

NTR-border-associated-macrophage-and-subclasses #2310

Closed
Closed
Show file tree
Hide file tree
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension

Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
91 changes: 65 additions & 26 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3023,6 +3023,10 @@ Declaration(Class(obo:CL_4040002))
Declaration(Class(obo:CL_4040003))
Declaration(Class(obo:CL_4040004))
Declaration(Class(obo:CL_4040005))
Declaration(Class(obo:CL_4042001))
Declaration(Class(obo:CL_4042002))
Declaration(Class(obo:CL_4042003))
Declaration(Class(obo:CL_4042004))
Declaration(Class(obo:CP_0000000))
Declaration(Class(obo:CP_0000025))
Declaration(Class(obo:CP_0000027))
Expand Down Expand Up @@ -3401,7 +3405,6 @@ AnnotationAssertion(oboInOwl:inSubset obo:CL_0000000 <http://purl.obolibrary.org
AnnotationAssertion(rdfs:comment obo:CL_0000000 "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one).")
AnnotationAssertion(rdfs:label obo:CL_0000000 "cell")
SubClassOf(obo:CL_0000000 obo:UBERON_0000061)
SubClassOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002160 obo:NCBITaxon_131567))

# Class: obo:CL_0000001 (primary cultured cell)

Expand Down Expand Up @@ -4519,7 +4522,6 @@ SubClassOf(obo:CL_0000112 obo:CL_0000540)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000113 "A vertebrate phagocyte with a single nucleus.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000113 "BTO:0001433")
AnnotationAssertion(rdfs:label obo:CL_0000113 "mononuclear phagocyte")
EquivalentClasses(obo:CL_0000113 ObjectIntersectionOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000113 obo:CL_0000518)
SubClassOf(obo:CL_0000113 obo:CL_0000842)

Expand Down Expand Up @@ -5505,7 +5507,6 @@ SubClassOf(obo:CL_0000218 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002377))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FB:ma") obo:IAO_0000115 obo:CL_0000219 "A cell that moves by its own activities.")
AnnotationAssertion(rdfs:label obo:CL_0000219 "motile cell")
EquivalentClasses(obo:CL_0000219 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048870)))

# Class: obo:CL_0000220 (obsolete cell by lineage)

Expand Down Expand Up @@ -5645,7 +5646,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000234 "BTO:0001044")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000234 "FMA:83806")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000234 "MESH:D010586")
AnnotationAssertion(rdfs:label obo:CL_0000234 "phagocyte")
EquivalentClasses(obo:CL_0000234 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909)))
SubClassOf(obo:CL_0000234 obo:CL_0000219)
SubClassOf(obo:CL_0000234 obo:CL_0000325)
SubClassOf(obo:CL_0000234 obo:CL_0000473)
Expand All @@ -5661,10 +5661,8 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000235 "MESH:D008264")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000235 "histiocyte")
AnnotationAssertion(rdfs:comment obo:CL_0000235 "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.")
AnnotationAssertion(rdfs:label obo:CL_0000235 "macrophage")
EquivalentClasses(obo:CL_0000235 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0031268)))
SubClassOf(obo:CL_0000235 obo:CL_0000113)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000235 obo:CL_0000766)
SubClassOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576))

# Class: obo:CL_0000236 (B cell)

Expand Down Expand Up @@ -7750,7 +7748,6 @@ SubClassOf(obo:CL_0000517 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000235))
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000518 "A phagocyte in vertebrates that is able to phagocytosis.")
AnnotationAssertion(rdfs:label obo:CL_0000518 "phagocyte (sensu Vertebrata)")
SubClassOf(obo:CL_0000518 obo:CL_0000234)
SubClassOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0002160 obo:NCBITaxon_7742))

# Class: obo:CL_0000519 (phagocyte (sensu Nematoda and Protostomia))

Expand Down Expand Up @@ -9710,11 +9707,7 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000738 "leucocyte")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000738 "white blood cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000738 "immune cell")
AnnotationAssertion(rdfs:label obo:CL_0000738 "leukocyte")
EquivalentClasses(obo:CL_0000738 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001667)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000738 obo:CL_0000988)
SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002405))
SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002160 obo:NCBITaxon_7742))
SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000037))

# Class: obo:CL_0000739 (obo:CL_0000739)

Expand Down Expand Up @@ -9975,7 +9968,6 @@ SubClassOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000547))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000766 "A cell of the monocyte, granulocyte, or mast cell lineage.")
AnnotationAssertion(rdfs:label obo:CL_0000766 "myeloid leukocyte")
EquivalentClasses(obo:CL_0000766 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000766 obo:CL_0000738)

# Class: obo:CL_0000767 (basophil)
Expand Down Expand Up @@ -10931,7 +10923,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000842 "FMA:86713")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000842 "mononuclear leukocyte")
AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000842 "peripheral blood mononuclear cell")
AnnotationAssertion(rdfs:label obo:CL_0000842 "mononuclear cell")
EquivalentClasses(obo:CL_0000842 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000842 obo:CL_0000738)

# Class: obo:CL_0000843 (follicular B cell)
Expand Down Expand Up @@ -11142,7 +11133,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000864 "FMA:84644")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000864 "fixed macrophage")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000864 "resting histiocyte")
AnnotationAssertion(rdfs:label obo:CL_0000864 "tissue-resident macrophage")
EquivalentClasses(obo:CL_0000864 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000479)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000864 obo:CL_0000235)

# Class: obo:CL_0000865 (gastrointestinal tract (lamina propria) macrophage)
Expand Down Expand Up @@ -11255,31 +11245,36 @@ SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000877 obo:CL_0000876
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16322748") obo:IAO_0000115 obo:CL_0000878 "A tissue-resident macrophage found in the central nervous system.")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000878 "CNS macrophage")
AnnotationAssertion(rdfs:label obo:CL_0000878 "central nervous system macrophage")
EquivalentClasses(obo:CL_0000878 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000878 obo:CL_0000864)

# Class: obo:CL_0000879 (meningeal macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11591794") obo:IAO_0000115 obo:CL_0000879 "A central nervous system macrophage found in the meninges (the three membranes that surround the brain). This macrophage types is highly phagocytic and expresses scavenger receptors.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11591794") Annotation(oboInOwl:hasDbXref "PMID:24078900") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_0000879 "A central nervous system macrophage that is part of the meninges. This macrophage types is highly phagocytic, expresses scavenger receptors, has dynamic protrusions and extends its processes during inflammation. The cell body of this macrophage is elongated and amoeboid spindle-shaped with limited mobility.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_0000879 "MM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_0000879 "MnMΦ")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") oboInOwl:hasExactSynonym obo:CL_0000879 "subdural leptomeningeal macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28323268") oboInOwl:hasExactSynonym obo:CL_0000879 "subdural meningeal macrophage")
AnnotationAssertion(rdfs:label obo:CL_0000879 "meningeal macrophage")
EquivalentClasses(obo:CL_0000879 ObjectIntersectionOf(obo:CL_0000878 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002360) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000879 obo:CL_0000878)
EquivalentClasses(obo:CL_0000879 ObjectIntersectionOf(obo:CL_4042001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002360) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000879 obo:CL_4042001)

# Class: obo:CL_0000880 (choroid-plexus macrophage)
# Class: obo:CL_0000880 (choroid plexus macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9550136") obo:IAO_0000115 obo:CL_0000880 "A central nervous system macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This cell expresses scavenger receptors.")
AnnotationAssertion(rdfs:label obo:CL_0000880 "choroid-plexus macrophage")
EquivalentClasses(obo:CL_0000880 ObjectIntersectionOf(obo:CL_0000878 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001886) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000880 obo:CL_0000878)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9550136") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_0000880 "A central nervous system macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This central nervous system macrophage expresses scavenger receptors, and has a star-like shaped body.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_0000880 "cpMΦ")
AnnotationAssertion(rdfs:label obo:CL_0000880 "choroid plexus macrophage")
EquivalentClasses(obo:CL_0000880 ObjectIntersectionOf(obo:CL_4042001 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001886) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000880 obo:CL_4042001)

# Class: obo:CL_0000881 (perivascular macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16507898") obo:IAO_0000115 obo:CL_0000881 "A central nervous system macrophage found in small blood vessels in the brain. Markers include CD14+CD16+CD163+.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16507898") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_0000881 "
A central nervous system macrophage that is part of small blood vessels in the brain. Markers include CD14, CD16, CD163. In homeostatic conditions, this central nervous system macrophage has a Non-motile cell body with extending and retracting projections through the blood vessel wall.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_0000881 "pvMΦ")
AnnotationAssertion(rdfs:comment obo:CL_0000881 "Markers: Human/monkey, mice: CD163. Human: CD14+CD16+CD163+.")
AnnotationAssertion(rdfs:label obo:CL_0000881 "perivascular macrophage")
EquivalentClasses(obo:CL_0000881 ObjectIntersectionOf(obo:CL_0000878 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925)))
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000881 obo:CL_0000878)
EquivalentClasses(obo:CL_0000881 ObjectIntersectionOf(obo:CL_4042001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925)))
SubClassOf(obo:CL_0000881 obo:CL_4033054)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000881 obo:CL_4042001)

# Class: obo:CL_0000882 (thymic medullary macrophage)

Expand Down Expand Up @@ -31920,6 +31915,50 @@ AnnotationAssertion(rdfs:label obo:CL_4040005 "mesenchymal stem cell of apical p
SubClassOf(obo:CL_4040005 obo:CL_0000134)
SubClassOf(obo:CL_4040005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003677))

# Class: obo:CL_4042001 (border associated macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasDbXref "PMID:37626977") obo:IAO_0000115 obo:CL_4042001 "A central nervous system macrophage that is part of the choroid plexus, meningeal and perivascular spaces. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier.")
AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042001 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042001 "2024-03-06T16:27:35Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36945367") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4042001 "BAM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4042001 "CAM")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") oboInOwl:hasExactSynonym obo:CL_4042001 "CNS-associated macrophage")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29426702") Annotation(oboInOwl:hasDbXref "PMID:37232741") rdfs:comment obo:CL_4042001 "A border associate macrophage expresses CD45 and CD11B. This cell is also known to have the following molecular signature: CD206, CD38, LYVE1, CD163, CD169")
AnnotationAssertion(rdfs:label obo:CL_4042001 "border associated macrophage"@en)
SubClassOf(obo:CL_4042001 obo:CL_0000878)

# Class: obo:CL_4042002 (stromal choroid plexus macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") obo:IAO_0000115 obo:CL_4042002 "A choroid plexus macrophage that is part of the choroid plexus stroma.")
AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042002 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042002 "2024-03-06T18:53:05Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4042002 "stromal cpMΦ")
AnnotationAssertion(rdfs:label obo:CL_4042002 "stromal choroid plexus macrophage"@en)
EquivalentClasses(obo:CL_4042002 ObjectIntersectionOf(obo:CL_0000880 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005206)))
SubClassOf(obo:CL_4042002 obo:CL_0000880)

# Class: obo:CL_4042003 (choroid epiplexus macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31061494") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_4042003 "A choroid plexus macrophage that is part of the apical surface of the choroid plexus epithelium. This macrophage has a star-like shaped body.")
AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042003 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042003 "2024-03-06T18:53:24Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31433571") oboInOwl:hasExactSynonym obo:CL_4042003 "Kolmer’s cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4042003 "cpepiMΦ")
AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4042003 "epiplexus cpMΦ")
AnnotationAssertion(rdfs:label obo:CL_4042003 "choroid epiplexus macrophage"@en)
EquivalentClasses(obo:CL_4042003 ObjectIntersectionOf(obo:CL_0000880 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003911)))
SubClassOf(obo:CL_4042003 obo:CL_0000880)

# Class: obo:CL_4042004 (dural macrophage)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31061494") obo:IAO_0000115 obo:CL_4042004 "A central nervous system macrophage that is part of the dura matter. This macrophage phagocytoses intruding pathogens and foreign molecules detected in the bloodstream or in the cerebrospinal fluid. This cell has an amoeboid body with dynamic protrusions in homeostasis.")
AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042004 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042004 "2024-03-07T11:09:00Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4042004 "dmMΦ")
AnnotationAssertion(rdfs:label obo:CL_4042004 "dural macrophage"@en)
EquivalentClasses(obo:CL_4042004 ObjectIntersectionOf(obo:CL_4042001 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002363) ObjectSomeValuesFrom(obo:RO_0000053 obo:CL_0000732)))
SubClassOf(obo:CL_4042004 obo:CL_4042001)

# Class: obo:CP_0000000 (obsolete CP:0000000)

AnnotationAssertion(obo:IAO_0100001 obo:CP_0000000 obo:CL_0017500)
Expand Down
Loading
Loading