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@GMELab Genetic and Molecular Epidemiology Laboratory

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    11 repositories

    • docker

      Public
      Dockerfile
      •0•0•0•0•Updated Mar 19, 2025Mar 19, 2025

    • StratMRAlgo

      Public
      An R-based software package which automates a stratified Mendelian randomization (MR) algorithm designed to identify effect modifiers of causal relationships
      R
      •
      GNU General Public License v3.0
      •0•1•0•0•Updated Mar 18, 2025Mar 18, 2025

    • lmutils.r

      Public
      Utilities for linear regression-based statistical computation, particularly in the same vein as methods like MonsterLM and RARity
      Rust
      •0•0•0•0•Updated Mar 7, 2025Mar 7, 2025

    • lmutils

      Public
      Utilities for linear regression-based statistical computation, particularly in the same vein as methods like MonsterLM and RARity
      Rust
      •
      MIT License
      •0•0•0•0•Updated Mar 3, 2025Mar 3, 2025

    • RARity

      Public
      A method to estimate rare variant heritability. Its versatility lies in the ability to estimate both gene-level and exome-wide heritability, in a fast, accurate, and unbiased manner.
      R
      •
      GNU General Public License v3.0
      •0•2•0•0•Updated Jan 15, 2025Jan 15, 2025

    • plots.r

      Public
      Generate beautiful forest plots with ease
      R
      •
      Other
      •0•0•0•0•Updated Jan 6, 2025Jan 6, 2025

    • phewmr-filter-snps

      Public
      Rust
      •
      MIT License
      •0•0•0•0•Updated Dec 22, 2024Dec 22, 2024

    • MonsterLM

      Public
      A method to estimate the proportion of variance explained by heritability and gene-by-environment interactions, in a fast, accurate, efficient, and unbiased manner on biobank-scale datasets (N>300,000).
      Shell
      •
      GNU General Public License v3.0
      •0•1•2•0•Updated Apr 3, 2024Apr 3, 2024

    • RV-EXCALIBER

      Public
      A methodological framework to conduct a calibrated gene-based rare variant association test by leveraging the genome aggregation database (gnomAD) as an external control dataset
      Shell
      •
      GNU General Public License v3.0
      •1•9•1•0•Updated Mar 4, 2023Mar 4, 2023

    • AutoMitoC

      Public
      Automatic Mitochondrial DNA Copy Number (mtDNA-CN) Pipeline to infer mtDNA-CN from SNP array intensities
      R
      •
      GNU General Public License v3.0
      •3•4•1•0•Updated Feb 14, 2022Feb 14, 2022

    • GraBLD

      Public
      an R based software package that makes polygenic traits prediction using gradient boosted and LD adjusted gene score weights.
      R
      •
      Other
      •4•10•0•0•Updated Apr 9, 2019Apr 9, 2019