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3000034

Clair Blacketer edited this page May 5, 2021 · 2 revisions

3000034 - Microalbumin [Mass/volume] in Urine

Albumin is a non-glycoslyated protein that comprises >50% of plasma proteins in plasma, cerebrospinal fluid, and urine. Concentrations of albumin in urine between 20-300 mg/L are considered microalbuminuria and indicate early signs of kidney damage, usually from diabetes.[^1] Albuminuria is characterized as urine albumin >300 mg/L and indicates overt kidney disease.[^2]

In the OMOP vocabulary 3000034 is a Standard Concept that represents the measurement Microalbumin [Mass/volume] in Urine

The recommended low and high values for each unit associated with 3000034 are below. These are not meant to be normal values. Rather, these are meant to be biologically plausible values. For example, it would be implausible to see a patient with a weight of 0 kg though a person could be 2.5 kg.

8715

In the OMOP vocabulary 8715 is a Standard Concept that represents the unit milligram/Liter (mg/L)

Plausible Low Value

0.0

Plausible High Value

3500.0

Rationale

Technically, microalbuminuria is defined as albumin measurements <300mg/L in urine and 300mg/L is the limit of how much albumin a urine dipstick will detect. However, it is possible that a person would have an albumin measurement >300mg/L. It is for that reason the plausible high value was set to 4000mg/L.[^3] While not technically microalbuminuria, patients with severe kidney dysfunction can exceed 4000mg/day or about 2500mg/L. An additional buffer of 1000mg/L to account for extreme high values was added to arrive at 3500mg/L

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