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3021119

Andryc edited this page May 14, 2021 · 1 revision

3021119 - CALCIUM.IONIZED [MOLES/VOLUME] IN BLOOD

Low ionized calcium levels are common in critically ill patients with sepsis, renal failure, cardiac failure, pulmonary failure, post-surgery or burns. Monitoring of ionized calcium is particularly important in the unconscious or anesthetized patient, in whom unrecognized changes in calcium homeostasis may result in serious cardiovascular dysfunction with little of no prior warning signs. Decreased ionized calcium levels between 3 and 4 mg/dL are usually well tolerated, but the risk of cardiac arrest increases when ionized calcium levels approach 2.5 mg/dL. An ionized calcium level below 2.8 mg/dL is a reasonable threshold to begin calcium replacement therapy. Patients with hypotension or low cardiac output may require calcium replacement when ionized calcium falls below 3.2 to 3.6 mg/dL. Ionized calcium levels should be monitored during replacement therapy. [1]

The Universetiy of Iow Department of Pathology notes a reference range of: [2]

  • Adults: 3.8 mg/dL - 5.2 mg/dL (.211 mmol/L - .2889 mmol/L)
  • Neonatal (0-5 days): 4.2 mg/dL - 5.9 mg/dL (.2333 mmol/L - .3278 mmol/L)

In the OMOP vocabulary 3021119 is a Standard Concept that represents the measurement CALCIUM.IONIZED [MOLES/VOLUME] IN BLOOD

The recommended low and high values for each unit associated with 3021119 are below. These are not meant to be normal values. Rather, these are meant to be biologically plausible values. For example, it would be implausible to see a patient with a weight of 0 kg though a person could be 2.5 kg.

8753

In the OMOP vocabulary 8753 is a Standard Concept that represents the unit MILLIMOLE PER LITER

Plausible Low Value

0.001

Plausible High Value

1.65*

Rationale

The range 0.001-1.65 was chosen based on values seen in real world data. There are a number of outliers seen in this measurement likely due to source data entry mis-types and/or meaurement mis-labeling. In the data reviewed more than 99% of data with this standard unit concept should be accounted for.

References

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